Deep brain stimulation of the subthalamic nucleus is a clinically effective tool for treating medically refractory Parkinson’s disease, but its neural mechanisms remain debated. Previous work has demonstrated that STN DBS results in evoked potentials in the primary motor cortex, suggesting that modulation of cortical physiology may be involved in its therapeutic effects. Due to technical challenges presented by high-amplitude DBS artifacts, these EPs are often measured in response to low-frequency stimulation, which is generally ineffective at PD symptom management. This (...) study aims to characterize STN-to-cortex EPs seen during clinically relevant high-frequency STN DBS for PD. Intraoperatively, we applied STN DBS to 6 PD patients while recording electrocorticography from an electrode strip over the ipsilateral central sulcus. Using recently published techniques, we removed large stimulation artifacts to enable quantification of STN-to-cortex EPs. Two cortical EPs were observed – one synchronized with DBS onset and persisting during ongoing stimulation, and one immediately following DBS offset, here termed the “start” and the “end” EPs respectively. The start EP is, to our knowledge, the first long-latency cortical EP reported during ongoing high-frequency DBS. The start and end EPs differ in magnitude and latency, and the end, but not the start, EP magnitude has a significant relationship to ongoing high gamma power during the EP. These contrasts may suggest mechanistic or circuit differences in EP production during the two time periods. This represents a potential framework for relating DBS clinical efficacy to the effects of a variety of stimulation parameters on EPs. (shrink)

Violence has been linked to the co-occurrence of cognitive dysfunction and altered activations in several brain regions. Empirical evidence demonstrated the benefits of acute exercise on motor inhibition and error detection and their neuronal processing. However, whether such effects also hold for the population with violent behaviors remains unknown. This study examined the effects of acute aerobic exercise on inhibitory control and error monitoring among violent offenders. Fifteen male violent offenders were counterbalanced into experimental protocols, which comprised a 30-min moderately (...) aerobic exercise [60% heart rate reserve] and a 30-min reading control session. After each session, participants performed an emotional stop signal task while event-related potentials were recorded simultaneously. Results showed insignificant changes in ERPs components [i.e., N2, P3, error-related negativity, and error-positivity amplitudes] and the behavioral performance in go condition, stop accuracy, and post-error adjustments by exercise. However, the current study demonstrated that the acute exercise facilitated stop signal reaction time when compared to the control session regardless of emotional conditions. This is the first research to exhibit the improvements in inhibitory performance by acute exercise for violent offenders. Most importantly, this effect was independent of affective settings, expanding the existing knowledge of the influences of acute exercise on cognition. Our findings implicate the perspective of acute exercise for clinical and correctional practices. (shrink)

P. KOnig: Einleitung - P. ZIche: Idiographik und allgemeine Wissenschaftlichkeit - Windelband und die Wissenschaftsreflexion um 1900 - G. HArtung: Ein Philosoph korrigiert sich selbst - Wilhelm Windelbands Abkehr vom Relativismus - O. SChlaudt: Philosophie am Leitfaden der Empirie. WIndelbands relativistisches Programm - S. KUft: Windelbands Konzeption von Transzendentalphilosophie und ihr Bezug zur Kulturphilosophie - R. BOnito Oliva: Windelband. KUlturphilosophie und Kulturkrise - P. KOnig: Teleologie und Geschichte bei Wilhelm Windelband - J. BOhr: Im Fortschreiben der Probleme: Windelbands 19. JAhrhundert (...) - T.-H. CHang: Der Wertbegriff beiWilhelm Windelband und sein Konzept der Problemgeschichte - T. KUbalica: Die Geschichte der Philosophie als Problemgeschichte - J. MEhlich: Windelbands Praludien und das Silberne Zeitalter in Russland - G. SChluter: Windelbands italienische Kontakte und Bezugnahmen - D. STefanelli: Notizen uber Karl Vossler und die "Sudwestdeutsche Schule" - C. ZAnfi: Geschichte, Natur und Leben: Windelband und Bergson in der Historismus-Debatte - J.-I. LIndén: Der beseelte Geist: Dilthey als Kritiker der badischen Schule - H. GUndlach: Windelbands Ringen mit der Psychologie - Anhang: Wilhelm Windelband: Blaue Hefte zur Psychologie. (shrink)

Strohal, R. Parmenides und das "Sein".--Erismann, T. Erkenntnis und Sein.--Jacoby, G. Die ontologischen Grundlagen des psychophysischen Problems.--Kohler, I. Grenzen der Psychologie.--Mayer-Hillebrand, F. Über Bedeutung und Berechtigung der Normwissenschaften.--Meister, R. Handlungen, Taten, Werke als psychische Objektivationen.--Oberhammer, G. Metaphysik und Mystik bei Plotin.--Pechhacker, A. Vérités de fait, vérités éternelles.--Scheffler, P. Wohlklang und physikalische Gesetzmässigkeiten.--Schlismann, A. Wort und Wirklichkeit.--Windischer, H. Das Transzendieren als Problem der neueren Ontologie.--Wohlgenannt, R. Politische Wirklichkeit und philosophische Erkenntnis.

The article is devoted to the problem of studying the relationship between language and ethnic culture. It analyzes Bashkir toponyms associated with the cult of fire. The Bashkirs, like many nations, including the Turkic and Mongolian, have thought that fire symbolized home and was the protector of the family. The Bashkirs worshiped fire as cleansing and healing power, while at the same time the fire represented formidable and dangerous force. Fire in the Bashkir mythology is closely related to its opposite (...) element - Water, with the gods of the upper world - the Sun and the Moon and the deity of Earth, geographical names of Bashkortostan testify this. On the material of Bashkir toponymy and related beliefs it was attempted to do a semantic etimological-onomasiological reconstruction of the Bashkir deity of fire Otukan, which dates back to the old Turkic deity Yduk Otuken//Otukan. In Mongolian mythology, it corresponds to the deity Etugen//Otuken, associated with the cult of the mother goddess, earth and fire, and in Japanese mythology - with the god, the owner of the land, - Ootukonu-si-no kami. According to the author, the formation of names connected with ‘fire‘ in the Bashkir toponymy was promoted by the worship of the deity of fire, the tribal fire, the tribal habitat and the family by Tatar-Mongols. Interesting is the fact, that the base ‘ut‘, which is connected with the ancient Turkic beliefs, also builds a theonym, a toponymic term, a geographic name, an ethnonym and anthroponym, i.e. it permeates the entire onomastic and appellative vocabulary. However, at the appellative level, this lexical item has no religious significance. For example, Otukan, TÓ©kÓ©n, Ò®tәgәn, Ò®tәk, otaq in Turkic languages have the meanings of ‘home‘, ‘yurt‘, ‘mountain valley‘, ‘flat place in the mountains on the hillside‘, ‘southern winter quarters‘. This relationship is explained by the fact that, initially, perhaps, yet there was the worship of a female deity Otukan that embodied fire and was associated with the earth, with the habitat and the ancestral hearth, where the original base morpheme was ‘fire‘, then it was associated with the deification of family and tribal territory, and later with the deification of the person of the ruler, this lexic item has spread throughout the onomastic vocabulary and in the appellative lexicon within the meaning of the place of residence. (shrink)

1. Sae sidae rŭl yŏrŏ gan saramdŭl -- 2. Ŏdum ŭi sidae.

1. Kwŏnil - Kwŏno -- 2. Kwŏnyuk - Kwŏnsip-il -- 3. Kwŏnsip-i - Kwŏnsip-ch'il.

It is common knowledge that many problems in contemporary physics, particularly in microphysics and cosmology, present various infinities of which it is difficult to dispose, and that their role in mathematics is so considerable that it is often defined as the discipline of the infinite. Therefore it would be difficult to deny that infinity exists. But it is just as well known that, over the entire history of science, recognition of infinity has resulted in various difficulties, contradictions, aporias, antinomies, paradoxes (...) — in a word, "much that is impossible," as Aristotle puts it. As phrased by one of the outs tanding mathematicians of the last century, David Hilbert, infinity offers a real challenge to our thinking. (shrink)

In recent years, as a result of the extensive employment of the ideas and methods of mathematical logic in cybernetics and computer mathematics here and abroad, there has been a noticeable rise in interest in the methodological problems of this science. One of these is the problem of the relations between mathematical logic and traditional and even modern formal logic. However, when this problem is discussed in our philosophical literature it appears to us that three of its significant factors are (...) neglected by many writers. (shrink)